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Apartments for Rent in Medical Center South

2,978 Rentals
.
  5. $202 Off
    Price Drop. $202 Off
    |
    1 BED
    $999+
    2 BEDS
    $1,499+
    3 BEDS
    $1,749+

    Lakes at 610

    9111 Lakes at 610 Dr, Houston, TX 77054
    (346) 414-0518
  15. Exceptional Value
    |
    STUDIO
    $1,339+
    1 BED
    $1,619+
    2 BEDS
    $1,269+
    4 BEDS
    $1,199+

    Life Tower

    6919 Main St, Houston, TX 77030
    (832) 803-0320
Showing 42 of 695 results, Page 1 of 17

Houston at a Glance

Average Rent

N/A
(All bedrooms and property types)
0

School Rating

out of 10 Rating
Learn more about
Schools in Houston
39

Some Transit

out of 100 TransitScore® Rating
Learn more about
Transportation in Houston
62

Somewhat Bikeable

out of 100 BikeScore® Rating
Learn more about
Transportation in Houston

Astrodome Neighborhood

The Astrodome is one of Houston’s most well-known areas and is home to several large attractions including the Reliant Stadium and Reliant Area. In the heart of downtown Houston, the Astrodome area is blocks away from Main Street which is one of the city’s busiest cultural centers.

Though heavily trafficked, this area has pedestrian-friendly sidewalks and has one of the southern-most stops on the Houston METRO rail line. This public transportation route runs north to south through Rice University, the Museum District and ends at Minute Maid Park, home to the Houston Astros Major League Baseball team.

This neighborhood is mostly commercial with the Reliant Area making up over half of the surface. Once considered a blighted area, developers constructed upscale apartment buildings beginning in the late 1990s that take up the rest of the land today. These complexes offer amenities like tennis courts and swimming pools and most are gated communities.

In the 77054 zip code, Almeda Road acts as the Astrodome’s eastern boundary. Holly Hall Street is the southern boundary of the neighborhood with Interstate Highway 610 only a few blocks further to the south. The University of Texas Health Science Center is located to the northeast. This along with the Intracare Medical Center, Methodist Hospital, Woman’s Hospital and University Medical Center make this area part of the medical district of Houston.

The namesake of the neighborhood, the Reliant Astrodome is home to the Houston Texans, one of two National Football League member teams in the state of Texas. The Texans play on the football floor or the Astrodome which also has floors dedicated to baseball and concerts. Reliant Park is the larger space for the Astrodome and also houses the Reliant Arena, Reliant Center and Reliant Stadium.

Top Budget-Friendly Neighborhoods in Houston

(For 1 bedroom apartments)

Average Rent in Nearby Cities

(For 1 bedroom apartments)

Getting Around Houston

Transportation

57

Somewhat Walkable

out of 100 WalkScore® Rating
You might be able to get out and walk when living in this area. Some errands can be accomplished on foot, but for others you need a car.
62

Bikeable

out of 100 BikeScore® Rating
You might be able to find places to ride your bike in this area, but you'll most likely want your car for most errands.
39

Some Transit

out of 100 TransitScore® Rating
You'll likely want a car when living in this area since it has few transit options.
Scores provided by Walk Scoreⓘ

Education

Data provided by GreatSchools.org 2025 © 2025. All rights reserved.

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